Ascione's Pharmacy in East Harlem was located in what was once a large #Italian enclave east of Lexington Avenue. By the 1930s, 110,000 Italians lived in this neighborhood. During the 1940s and 1950s due to severe overcrowding in the area, many Italians moved out and Puerto Ricans became the dominant group. We love this amazing #vintage #signage with #script lettering on porcelain enamel tiles. Photo from 2003 appears in our book "Store Front: The Disappearing Face of New York".